Friday, January 24, 2020

Essay --

Proteins control all biological systems in a cell. Some proteins are able to perform their tasks independently; while many other proteins within a cell interact with other proteins to function properly. Protein interactions within a cell regulate cell behavior at a systems level. Thus, elucidating the structure and dynamics of protein interaction networks in vivo is a central goal in biology. The identification of the protein interaction networks (PINs) inside a cell is crucial to understanding the fundamental questions about how a cell is able to organize matter, information and energy transformations to preform specific functions at a biochemical level. The discovery of novel protein-protein interactions and determining how these proteins function in a network is fundamental to understanding biological systems. This new way of studying biological systems is called interactomics. While several genomes of different species have been sequenced, many proteins that are encoded in the genome have yet to have their function or relevance determined. Although there is an increasing importance to map out protein interaction networks, the actual detection of protein-protein interactions is complicated. Proteins have various charges and numerous secondary and tertiary structures they can fold into. Also, there are countless parameters that can change their interactions with other proteins in the cell. Furthermore, many protein-protein interactions can be transient, in that they only are short lived or require specific condition to facilitate their interaction with other proteins. Several Methods have been used to study protein-protein interactions. However, one rarely addressed question is whether protein-protein interactio... ... broad overview of the structural and functional networks within a living cell. However, there are plenty more areas of the interactome that can be explored, such as the dynamics of the interactions as well as how different growth condition affect protein interaction networks. Also, a wide variety of different reporter genes can be used to study temporal and spatial interactions over a comprehensive range of time periods as well as other distresses. Furthermore, since the PCA can provide a reference for spatial dynamics of different protein-complex topologies since it is able to generate a map at 8nm resolution. The integration of the results found using the PCA technique with gene regulation dynamics and protein modification can lead to a better understanding about how cellular processes are organized at a molecular and structural level within a living cell.

Thursday, January 16, 2020

Ownership of Media Companies – Disney, the BBC and The Bath Chronicle

Disney’s a pubic company and is also a conglomerate it has a net income of around $4.555 billion and has share’s of 1.856 billion. As Disney is publicly owned it means that their disadvantage is that they have to follow many people or a charter like the BBC. They also have an disadvantage with limited liability as they are personal labially. Public companies also means they have another disadvantage as they have higher costs for the government which means they have higher taxes. Mainly they do have to share financial documents with the public which also means that competition does get to see there documents. Finally being a public company you dot have to ask lots of shareholders what they think. On the other hand the advantages could be that it provides more jobs. They have to provide a service for the whole country. Disney ventures Disney has many business venture’s and own many companies including 9 walt Disney picture companies for example Touchstone, 5 Disney music companies, Television channels, cable networks, ESPN, Disney interactive groups, holidays and theme parks. Disney are making so many things and spreading their wings into so many different business. With all these business’s it help’s Disney have a massive vertical integration. Disney is well renowned for it’s classical movies and recent movies from the likes of Snow White and Cinderella to Tangled and Princess and the frog. Disney also want’s to travel into different countries and they do this by making cultural movies and having Disney holidays, theme parks and cruises. Whilst Disney make’s many movies we love they have also been criticized for being sexist, ageism and sometimes racist, for example the villain is always old and the princess always being a type of housewife, for example Snow White cleaning the house. In films like Aladdin a song featured in the movie featured a quite rude ‘I come from a land†¦where they cut off your ears, if they don’t like your face. It’s barbaric, but hey, it’s home.’ When you think of Disney you think fun, light family entertainment not Disney being excused racist, sexism and ageism but in a quote this quote Michael Eisner explains â€Å"We have no obligation to make history. We have no obligation to make art. We have no obligation to make a statement. To make money is our only objective.† Disney use has very good vertical integration due to how many companies they own. Disney can make movies with their production company, advertise the films and products in their magazine, show it on their television channel. For example Beavis and Butt-Head Do America on costed $11 million to make and made a profit on $70 million, but Disney’s The Lion King made a profit of $1 billion due to them making merchandise, TV show, broadway shows. When films are made by conglomerates they generate more profit than a box office filmed would. Ownership BBC ownership BBC The BBC is neither public nor privately owned, it is a trust and is funded by license payers. On the BBC trust website it has in bold letters ‘getting the best out of the BBC for license fee payers’. This means that the BBC has a charter which tells the BBC the do’s and don’ts. The charter tells the BBC that the content on the BBC must be informative, educational, entertaining and the BBC should â€Å"Bring the UK to the world and the world to the UK†. As the BBC is a trust and run’s on the money that the incense payer give’s them, the BBC can just use the money they make on TV shows etc and put it into other shows they make. The advantage of a trust is that the money can just reused however the disadvantage is that the it has a charter that it must run by however I also see this as a positive ting because they know what things they are supposed to do. BBC services The BBC has multiply TV stations, radio stations, news channels and many other sector’s including online services, interactive media, music, miscellaneous etc Personally I like the BBC because 1. It has no adverts and I suppose the BBC don’t need adverts of products because the BBC is paid for by links payers and people that watch TV mostly hate adverts. However they do play adverts for programs on the BBC. This may increase viewers as it allows them to skip the things they don’t like but also the BBC has some of the best shows on the TV. Since the digital switch over I can only imagine that the BBC lost viewing figures. With the BBC becoming a trust in 2007, I think that the this has helped the BBC run a more organised service. It has gave the BBC strategy and overall it has made the BBC more successful. Since the trust came in in 2007 the trust has approved new services including iPlayer, HDTV, BBC Alba and the digital switchover. Ownership Bath Chronicle The Bath chronicle The Bath chronicle is a public company which means that it has the same advantages and disadvantages of Disney. However as Disney is much bigger, this means the rules are probably less important but still are still used. The newspaper which began in 1760 is now owned by Northcliff media. As the chronicle is a newspaper it must write about things in Bath but it can mention some major things outside Bath but most of the stories are based around local area. So I suppose this must be an advantage as they still have some freewill. I suppose that Northcliff media has Horizontal integration as they buy all different newspapers. The advantage of this can be that they can share the costs of production and management, the production can be done in bulk but may be a bit harder then a TV station or other media sector, as local papers may be made locally and have different content and deadlines and profits could be more. On the other hand disadvantages could include individuality being lost, no competitors left like a monopoly when there’s a lack of competition.

Wednesday, January 8, 2020

The Philosophy Of The Bible Essay - 1618 Words

â€Å"Behold, children are a heritage from the Lord, the fruit of thy womb a reward. Like arrows in the hand of a warrior are the children of one’s youth. Blessed is the man who fills his quiver with them!† (Psalm 127:3-5, English Standard Version) Foundation for Discipline Parenting children can be a joy and a challenge. Parenting is not for wimps. Most parents desire to raise their children as a productive member of our society. In able to successfully do this, parents that identify themselves as believers need to study the bible and determine how to biblically discipline. The bible needs to be their foundation. There are several verses throughout scripture that discuss discipline. â€Å"Whoever spares the rod hates his son, but he who loves him is diligent to discipline him. â€Å"(Proverb 13:24, English Standard Version) â€Å"Folly is bound up in the heart of a child, but the rod of discipline drives it far from him.† (Proverb 22:15, English Standard Version) â€Å"Do not withhold discipline from a child; if you strike him with a rod, he will not die.† (Proverb 23:13, English Standard Version) Discipline your son, and he will give you rest; he will give delight to your heart. (Proverb 29:17, English Standard Version) Fathers, do not provoke your children to anger, but bring them up in the discipline and instruction of the Lord. (Eph. 6:4, English Standard Version) You shall beat him with a rod, and deliver his soul from hell (Proverb 23:14, English Standard Version) The verses above areShow MoreRelatedThe Philosophy Of The Bible1560 Words   |  7 Pagesbusiness has been long neglected as an important avenue to Glorify God. In this book Professor Grudem turns his attention to areas that were unlikely to provoke controversy or offense. In my opinion the main idea or impression of this book is that the bible teaches as well as, shows us that profitable, productive, and competitive business is an important way Christians should glorify God. This text explains that the following theories were created by God. The first theory that the Professor has writtenRead MoreAugustine s Confessions : A Diverse Mix Of Autobiography, Philosophy, And Interpretation Of The Christian Bible1304 Words   |  6 PagesSaint Augustine’s Confessions is a diverse mix of autobiography, philosophy, and interpretation of the Christian Bible. 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